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New compound offers attractive therapeutic candidate for autoimmune inflammatory diseases

Leiden University has identified a new adenosine receptor agonist. The innovative technology that led to its design, synthesis and pre-clinical evaluations, is now available for licensing purposes and/or for collaborative therapeutic development in the area of autoimmune inflammatory diseases.

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Novel compound offers new treatment approach for ovarian cancer

A novel compound against ovarian and other cancers has been isolated from the leaves of an Australian native plant belonging to the family of Compositae. This family is known for its natural products, including sesquiterpene lactones (SLs). To date great interest is shown for the potential of SLs as anticancer agent. Different fractions of the crude plant extract were tested in vitro against ovarian cancer cell lines and other cancer cell lines. Fractions with clear cytotoxic effects were selected and further analysed. A compound could be isolated by 1HNMR, 13CNMR and ESI mass spectrometry.

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