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Leiden University has identified
a new adenosine receptor agonist. The innovative
technology that led to its design, synthesis and
pre-clinical evaluations, is now available for
licensing purposes and/or for collaborative
therapeutic development in the area of autoimmune
inflammatory diseases.
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A novel compound against
ovarian and other cancers has been isolated from
the leaves of an Australian native plant
belonging to the family of Compositae. This
family is known for its natural products,
including sesquiterpene lactones (SLs). To date
great interest is shown for the potential of SLs
as anti‐cancer
agent. Different fractions of the crude plant
extract were tested in vitro against ovarian
cancer cell lines and other cancer cell lines.
Fractions with clear cytotoxic effects were
selected and further analysed. A compound could
be isolated by 1H‐NMR,
13C‐NMR
and ESI mass spectrometry.
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