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Promising blood biomarkers identified for colorectal cancer: Is a screening blood test within reach?

The search for blood-borne biomarkers that could be used to screen for colorectal cancer (CRC) has uncovered two promising candidates that may one day lead to the development of a simple blood test. Scientists have been piecing together the molecular events involved in the development of CRC and have identified abnormal DNA methylation patterns and the presence of microRNAs as major players in the carcinogenic process.

 
     
    Biosimilars one of the most promising segments of European pharma industry, says KuickResearch

Biosimilars are one of the most promising segments of the European pharma industry, according to a report by market research company KuickResearch. It found that the expiration of patents on blockbuster drugs, amenable regulatory framework and economic incentives have driven steady growth in the sector.

 
     
  J&J brings its Care4today mobile adherence programme to the UK  
  Lilly invests in UK life sciences via biotech fund  
  GSK plans to sell off older products  
  AstraZeneca rejects Pfizer's final £69bn takeover bid  
  As Pfizer fights it out in Britain, US lawmakers are making their move in the long game  
     
   
 
 
 
 
 

 

MorphoSys to Receive Milestone Payment for Guselkumab Phase 3 Program

 

 

 

GW Pharmaceuticals Announces Epidiolex(R) Receives Orphan Designation From European Medicines Agency for the Treatment of Dravet Syndrome

 
   

 

Virax to acquire deep AKT inhibitor portfolio already in Phase 1b/2 breast & Phase 1b ovarian cancer trials

 

 

 

MorphoSys Acquires Lanthipeptide Technology from Lanthio Pharma

 

 

 

Auspherix and Domainex Announce Collaboration to Develop New Drugs to Treat Antibiotic-resistant Bacterial Infections

 

 
 
  KCR Date Forecaster App for Easier Scheduling of Medical Appointments  
   
 
  GW Pharmaceuticals Announces New Physician Reports of Epidiolex(R) Treatment Effect in Children and Young Adults With Treatment-Resistant Epilepsy  
   
 
  Surgical Specialties Adds New Equity Partner and CEO  
   
 
  Oxford BioMedica Acquires Windrush Court Office and Laboratory Facilities  
   

 

Oxford BioMedica announces new process development and manufacturing collaboration which includes LentiVector® licence agreement

 
 
 
  A Cure for Ebola? These 3 Biotech Companies Are Working on It

 

Medical experts believe it was just a matter of time before Ebola made its way across the Atlantic to America. The first case in the U.S. was confirmed last week, and it's possible that there will be more cases in the future.

 

RCas9: A Programmable RNA Editing Tool

 

A powerful scientific tool for editing the DNA instructions in a genome can now also be applied to RNA, the molecule that translates DNA’s genetic instructions into the production of proteins. A team of researchers with Berkeley Lab and the University of California (UC) Berkeley...

Vitamin D significantly improves symptoms of winter-related atopic dermatitis in children

 

A study conducted in more than 100 Mongolian schoolchildren found that daily treatment with a vitamin D supplement significantly reduced the symptoms of winter-related atopic dermatitis, a type of eczema.

 
  Human genome was shaped by an evolutionary arms race with itself

 

New findings by scientists at the University of California, Santa Cruz, suggest that an evolutionary arms race between rival elements within the genomes of primates drove the evolution of complex regulatory networks that orchestrate the activity of genes in every cell of our bodies.

 
  Phosphate Increases The Concentration of Sodium (!) in The Blood

 

A previously undiscovered role played by the hormone FGF23 has now been discovered in a project funded by the Austrian Science Fund FWF. Scientists were already aware that greater quantities of this hormone are produced when there is too much phosphate in the blood plasma and that it reduces the absorption of this mineral from the urine.

 
  New enzyme targets for selective cancer therapies

 

Thanks to important discoveries in basic and clinical research and technological advances, the fight against cancer has mobilized into a complex offensive spanning multiple fronts. Work happening in a University of Alberta chemistry lab could help find...

 
  New insights into Ebola infection pave the way for much-needed therapies

 

The Ebola virus is among the deadliest viruses on the planet, killing up to 90% of those infected, and there are no approved vaccines or effective therapies. A study published by Cell Press on May 7th in the Biophysical Journal reveals how the most ...

 

Team determines structure of a molecular machine that targets viral DNA for destruction

 

With a featured publication in the Aug. 7 issue of Science, Montana State University researchers have made a significant contribution to the understanding of a new field of DNA research, with the acronym CRISPR, that holds enormous promise for fighting infectious diseases and genetic disorders.

 
  See-through organs and bodies will accelerate biomedical discoveries

 

The ability to see through organs and even the entire body to visualize long-range connections between cells as well as fine-grained cellular structures has been...

 
  A map for eye disease

 

Understanding eye diseases is tricky enough. Knowing what causes them at the molecular level is even more confounding. Now, University of Iowa researchers have created...

 
 
  Age of puberty in girls influenced by which parent their genes are inherited from

 

For the first time, Spanish researchers have detected an unknown interaction between microorganisms and salt. WhenEscherichia coli cells are introduced into a droplet of salt water and is left to dry, bacteria manipulate the sodium chloride crystallisation...

 
 
  Bacteria manipulate salt to build shelters to hibernate

 

For the first time, Spanish researchers have detected an unknown interaction between microorganisms and salt. WhenEscherichia coli cells are introduced into a droplet of salt water and is left to dry, bacteria manipulate the sodium chloride crystallisation...

 

Mechanism that prevents lethal bacteria from causing invasive disease is revealed

 

An important development in understanding how the bacterium that causes pneumonia, meningitis and septicaemia remains harmlessly in the nose and throat has been discovered at the University of Liverpool's Institute of Infection and Global Health.

  DNA origami nano-tool provides important clue to cancer

 

Researchers at Karolinska Institutet in Sweden have headed a study that has provided new knowledge about the EphA2 receptor, which is significant in several forms of cancer. This is important knowledge in itself – but just as important is how this study, which is published in the highly respected journal Nature Methods today, was conducted.

 

'Molecular movies' will enable extraordinary gains in bioimaging, health research

 

Researchers today announced the creation of an imaging technology more powerful than anything that has existed before, and is fast enough to observe life processes as they actually happen at the molecular level.

Over-activity of enzyme HDAC6 exacerbates symptoms of Amyotrophic Lateral Sclerosis

 

Scientists at VIB and KU Leuven have demonstrated in fruit-flies that over-activity of the enzyme HDAC6 in the nerve ends exacerbates the symptoms of the neurodegenerative condition Amyotrophic Lateral Sclerosis (ALS / Lou Gehrig's Disease). Inhibition of this enzyme could offer a protective effect against ALS.

 
  Decoding characteristic food odors

 

How are we able to recognize foodstuffs like strawberries, coffee, barbecued meat or freshly boiled potatoes by smell alone? Foodstuffs contain more than 10,000 different volatile substances. But only around 230 of these determine the odor of the food we eat. Narrowing it down further, between just 3 and 40 of these...

 
 

Scientists identify new pathogenic & protective microbes associated with severe diarrhea 

 

In a finding that may one day help control a major cause of death among children in developing countries, a team of researchers led by faculty from the University of Maryland, College Park and the University of Maryland School...

   
 
 
 
Evaluation of ADMET Drug Properties in Drug Discovery and Development
27- 28 January 2015
  The course will describe scientific concepts and practice of ADME and toxicology studies in drug development, including preclinical in vitro and in vivo studies, clinical studies, IND and NDA submissions, and analytical chemistry.
 
     
 
     
  Sanner surpasses 55 million Euro mark  
  Sanner GmbH, a manufacturer of high quality plastic packaging and components for pharmaceutical, medical and healthcare products, topped the 55 million Euro mark and set a new sales record in 2013 (2012: 50.6 million Euro). This development was supported by a clear brand positioning with the new slogan "Sanner. Protecting Health" and substantial national and international investments.  
     
       
     
    Nanion Starts Shipping the SyncroPatch 384 Patch Engine – a Revolutionary Instrument for Giga-Seal, Automated Patch Clamp-Based Ion Channel Drug Screening  
   

The brand-new SyncroPatch 384 Patch Engine (PE) now released by Nanion Technologies propels ion channel drug discovery to a new level. Designed for seamless integration into process-automated drug screening environments, the Patch Engine is equipped with 384 patch clamp amplifiers and an advanced 384 channel liquid handling robot.

 
       
   
     
  AdiStem Announces PhotoActivated PRP Getting Superb Results on Joint Pain  
 

AdiStem Ltd., a provider of PhotoActivation Technology and medical solutions that assist in orthopedic, cosmetic, neurologic, pulmonary, metabolic and plastic/reconstructive surgery procedures, announces today that photoactivated PRP (Platelet Rich Plasma) prior to injection reduces pain and accelerates healing.

 
     
       
       
       
 
How to Develop Stability Indicating HPLC Methods
29-30 September 2014
 
Evaluation of ADMET Drug Properties in Drug Discovery and Development
27- 28 January 2015
 
 
   
   
   
   
   
   
   
 
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